Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere
Conditions
Interventions
Intervention1: nil: nil
Sponsors
nil
Eligibility
Inclusion criteria
Inclusion criteria: Age above 18 years Patients with acute severe brain injury- traumatic brain injury (TBI), and stroke, aneurysmal subarachnoid hemorrhage (aSAH), intracranial hemorrhage undergoing invasive ICP monitoring at the discretion of the treating team along with invasive arterial blood pressure monitoring.
Exclusion criteria
Exclusion criteria: Refusal of consent to participate in the study Patients with medical or surgical history of pupillary or corneal abnormalities (such as post- ophthalmic surgical deformation, or ocular trauma) inability to perform the pupillary assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| correlate the estimated ICP eICP using non-invasive monitoring parameters i.e. ONSD, DAB, TCD, TCCD and pupillometry derived parameters, with the invasive ICP To identify the most accurate non-invasive method of eICP Timepoint: Patients admitted to the Neuro-ICU with an in-situ external ventricular drain EVD or Codman and arterial blood pressure monitoring will be enrolled. Invasive ICP will be recorded within 48 to 72 hours of ICP device insertion and ICU admission alongside non-invasive ICP estimation. Patients will be monitored for clinical changes in GCS with measurements repeated if there is a 2 point increase or decrease in GCS during icu stay and if evd or codman in situ. | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify the improvement in accuracy of eICP with the combination of the non-invasively derived parameters. Timepoint: Patients admitted to the Neuro-ICU with an in-situ external ventricular drain EVD or Codman & arterial blood pressure monitoring will be enrolled. Invasive ICP will be recorded within 48 to 72 hours of ICP device insertion & ICU admission alongside non-invasive ICP estimation. Patients will be monitored for clinical changes in GCS with measurements repeated if there is a 2 point increase or decrease in GCS during icu stay & if evd or codman in situ. | — |
Countries
India
Contacts
Public ContactDr Sushmitha A
NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES
Outcome results
None listed