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To evaluate and compare the efficacy of tablet Silodosin vs tablet Tadalafil for lower ureteric calculi expulsion

Effectiveness of Silodosin versus Tadalafil as medical expulsive therapy for lower ureteric calculi - A Randomised Controlled Trial - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082491
Enrollment
90
Registered
2025-03-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N201- Calculus of ureter

Interventions

Intervention1: Tablet Tadalafil: Tablet Tadalafil is given Per Oral at 5mg once daily after food for 4 weeks Control Intervention1: Tablet Silodosin: Tablet Silodosin is given Per Oral at 8 mg once d

Sponsors

Aarupadai Veedu Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient from 18 years to 60 years Both Genders Patients with ureteric calculi of size 5 to 10 mm in greatest dimension confirmed by CT-KUB and X-Ray KUB .

Exclusion criteria

Exclusion criteria: Patients not willing for study Patients with functional / anatomical abnormalities in ureter Patients with multiple ureteric stone Patients with Bilateral Ureteric stones Pregnant and Lactating mothers Patients with vertigo , cardiac abnormalities, hypotension

Design outcomes

Primary

MeasureTime frame
Effectiveness of Silodosin versus Tadalafil as medical expulsive therapy for lower ureteric calculiTimepoint: Expulsion of ureteric calculi at 0,2and 4 weeks

Secondary

MeasureTime frame
to find out difference in duration of time in Silodosin versus Tadalafil as medical expulsive therapy for lower ureteric calculiTimepoint: Expulsion of ureteric calculi at 0,2 & 4 weeks

Countries

India

Contacts

Public ContactDrKRavichandran

Aarupadai Veedu Medical College and Hospital

drkravichandranyadav@gmail.com9443091259

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 8, 2026