An introduction of autologous Platelet rich plasma in the socket of removed lower 3rd molar teeth and study of the healing with its use in medically fit patients.

An intervention of autologous Low Concentration Platelet Rich Plasma at surgically extracted mandibular 3rd molar site with a fractal viewpoint to scrutinize the changes - A pilot study. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082483

Enrollment

Registered

2025-03-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Autologous Low concentration of Platelet Rich Plasma: Autologous Low concentration of Platelet Rich Plasma will be introduced to the extraction site of impacted mandibular 3rd molar by

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II planned patients for surgical extraction of impacted mandibular 3rd molars without pathology.

Exclusion criteria

Exclusion criteria: Pathology associated with mandibular 3rd molar to be extracted. Patients with systemic conditions and diseases like Hypertension, Diabetes Mellitus, AIDS or immunosuppressive diseases, bleeding disorders, bone disorders; pregnant or lactating women; patients allergic to lidocaine, paracetamol or ibuprofen; patients in whom the administration of epinephrine is contraindicated, smokers, alcohol abuse, patients who presented with a jawbone-associated pathology and non-co-operative patients (psychic-motor dysfunction and behaviour disorders), ASA 3, 4 and 5

Design outcomes

Primary

Measure	Time frame
A better healing at the surgical site without reduced chances of post-op infection and trismus. Reduction in the perception of post-op pain which is a major factor causing discomfort to the patient. Rapid closure of the wound. Rapid bone formation thus with a greater amount of density and mineral contentTimepoint: 24 hours, 3rd day, 7th day, 14th day	—

Secondary

Measure	Time frame
1) Early epithelialisation of the wound. 2) reduction in pain . 3) increase in density of bone.Timepoint: 7th day, 14th day. 3 months	—

Countries

India

Contacts

Public ContactVaibhav Sheshrao Bibe

Meenakshi Ammal Dental college and Hospital, Chennai

drmanodh.omfs@madch.edu.in9804439655

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026