Skip to content

Cardiac Biomarkers and Sepsis : Understanding the Role of Troponin I

Correlation of High Sensitivity Troponin I with Severity of Sepsis in ICU : A Prospective Observational Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/03/082468
Enrollment
90
Registered
2025-03-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R652- Severe sepsis

Interventions

Intervention1: NIL: NIL

Sponsors

Dr Srijan Bhattacharjee
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with sepsis (Severe Inflammatory Response Syndrome with a proven or suspected source of infection)

Exclusion criteria

Exclusion criteria: 1)No informed consent given for the study. 2)Patient under coronary care(history of Coronary artery disease, Myocardial Ischaemia, coronary stent placement with or without medication). 3)Patients in immunosuppressed state (steroid treatment, Bone marrow or organ transplant patient, leukopenia, neutropenia). 4)Patients with haematological malignancy. 5)Patients with pre-existing autoimmune conditions, have received chemotherapy/radiotherapy. 6)Return of Spontaneous circulation post cardiac arrest patients. 7)Pregnant patients

Design outcomes

Primary

MeasureTime frame
To correlate high sensitivity Trop I values as a predictor of sepsis severity using SOFA score.Timepoint: Day 0,2,3 and last day of icu stay .

Secondary

MeasureTime frame
To study the relationship of high sensitivity Trop I values with other biomarkers - Procalcitonin - N Terminal Pro BNP - C Reactive protein (CRP) Timepoint: Day 0,2,3 and last day of icu stay.

Countries

India

Contacts

Public ContactDr Hiranya Kumar Saharia

Gauhati Medical College and Hospital

sahariahiranya@gmail.com9435087643

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026