Health Condition 1: Z468- Encounter for fitting and adjustment of other specified devices
Conditions
Interventions
Intervention1: Macintosh Laryngoscope, C-Mac Video Laryngoscope, Fiber optic Bronchoscope: compare biochemical markers pre and post intubation that is Serum Cortisol Serum Prolactin and HS CRP to str
Sponsors
Department of Anaesthesiology and Critical Care, JNMCH, AMU, Aligarh
Eligibility
Inclusion criteria
Inclusion criteria: Patients planned for elective surgery under general anaesthesia in JN Medical College and Hospital in time period between 2023-25, ASA Grade I & II, BMI 18-25Kg/sq.m, MP Grades 1 & 2
Exclusion criteria
Exclusion criteria: Previous history of multiple/ failed intubation, Predicted difficult laryngoscopy and intubation in MP equal to or more than 3 grade, Any pathology of the oral cavity that may obstruct the insertion of device, Mouth opening less than 2.5cm, Patient with any endocrine disorder or on any such concerned medications, Potentially full stomach patients like trauma, morbid obesity, pregnancy, history of gastric regurgitation and heart burn and at risk of esophageal reflux like hiatus hernia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare changes in serum cortisol level post intubation compared to pre induction using Direct Laryngoscope, Video Laryngoscope and Fiberoptic Bronchoscope.Timepoint: First baseline sample of Serum Cortisol will be taken during pre induction time and then second sample will be taken after 5 minutes of intubation, comparing three devices Direct Laryngoscope, Video Laryngoscope and Fiberoptic Bronchoscope. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare changes in serum prolactin, high sensitivity C reactive protein level post intubation compared to pre induction using the three devicesTimepoint: First baseline sample of Serum prolactin, high sensitivity C reactive protein level will be taken during pre induction time & then second sample will be taken after 5 minutes of intubation, comparing three devices Direct Laryngoscope, Video Laryngoscope & Fiberoptic Bronchoscope.;To compare haemodynamic changes.Timepoint: To compare haemodynamic changes post intubation compared to pre induction after 1,3, & 5 minutes of intubation.;To compare the time required for intubation.Timepoint: To compare the time required for intubation using the three devices in seconds;To compare the number of attempts required for intubationTimepoint: To compare the number of attempts required for intubation;To compare the success rate of intubationTimepoint: To compare the success rate of intubation;To compare the number of adjustment maneuvers required for successful intubation.Timepoint: To compare the number of adjustment maneuvers required for successful intubation. | — |
Countries
India
Contacts
Public ContactNishant Varshney
Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh
Outcome results
None listed