Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Modified Rotterdam criteria, in which PCOS may be diagnosed if any two of the following are present: (1) clinical or biochemical hyperandrogenism, (2) evidence of oligo-anovulation, (3) polycystic appearing-ovarian morphology on ultrasound, with exclusion of other relevant disorders. 2.Nonpregnant woman 3.Recently diagnosed PCOS participants 4.Willingness to participate in the study and provide informed consent
Exclusion criteria
Exclusion criteria: 1.Participants who are on oral contraceptive pills (OCP) 2.History of chronic systemic illness (DM, HT, TB, etc) 3.Subjects currently on medication against systemic diseases 4.Smokers and Alcoholic 5.History of cardiovascular or cerebrovascular disease. 6.Pregnancy or planning pregnancy during the study period. 7.Use of medications that could affect vascular function (e.g., anticoagulants). 8. Women who did not consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Decrease in arterial stiffness (measured by pulse wave velocity and augmentation index). 2. Decrease in serum homocysteine levels. Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Decrease in Blood Pressure 2. Change in Body Composition( measured by BMI, waist circumference, Waist to hip ratio) 3. Change in Quality of Life (assessed by FertiQOL and Pittsburgh Sleep Quality Index questionnaire) 4. Better Heart Rate VariabilityTimepoint: 3 months | — |
Countries
India
Contacts
All India Institute of Medical Sciences, Mangalagiri