A clinical trial to study the effects of Aspirin in patients with aneurysmal subarachnoid haemorrhage

Effects of Aspirin on postoperative cerebral vasospasm and delayed cerebral ischemia in aneurysmal subarachnoid haemorrhage A prospective, randomized, single-blinded pilot trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082356

Enrollment

Registered

2025-03-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I60- Nontraumatic subarachnoid hemorrhage

Interventions

Intervention1: Treatment group: Aspirin 75mg OD HS for 14 days with Nimodipine 60mg Q6H will be administered to patients in the intervention group Control Intervention1: Control group: Nimodipine 60mg

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Patients visiting the AIIMS Jodhpur emergency or OPD or admitted under the Department of Neurosurgery in the study duration 2. Age above 18 years, and 3. Patients with SAH caused by ruptured intracranial aneurysm

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Patients with non aneurysmal SAH 2. Patients with known allergy to aspirin 3. Pregnancy 4. Patients with known bleeding diathesis

Design outcomes

Primary

Measure	Time frame
Aspirin decreases the incidence of postoperative cerebral vasospasm and delayed cerebral ischaemia in patients with aneurysmal subarachnoid haemorrhageTimepoint: Outcomes will be assessed and compared at 3 months	—

Secondary

Measure	Time frame
improved quality of life and decreased morbidity of patientsTimepoint: aspirin by preventing cerebral vasospasm and delayed cerebral ischaemia will decrease the morbidity and improve the quality of life after the surgery	—

Countries

India

Contacts

Public ContactAdvait Pakhmode

AIIMS jodhpur

advaitpakhmode17007@gmail.com9511699859

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026