Health Condition 1: F05- Delirium due to known physiological condition
Conditions
Interventions
Intervention1: Melatonin: 5-10 milligram OD for 7 days
Intervention2: Lemborexant: 5-10 milligram OD for 7 days
Control Intervention1: Placebo: Not applicable
Sponsors
Praveen Rikhari
Eligibility
Inclusion criteria
Inclusion criteria: 1. Those who will be diagnosed with delirium according to ICD-11 2. Those whose primary caregivers will provide written informed consent
Exclusion criteria
Exclusion criteria: 1. Substance withdrawal delirium 2. Postictal confusion/state 3. Patients who will be comatose 4. Intubated patients/Patients on complete mechanical ventilatory support 5. Those with severe hepatic impairment (Child-Pugh Class C) 6. Those scheduled for surgery 7. Patients who will be unable to take oral drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Memorial Delirium Assessment Scale ScoreTimepoint: 4th Day, 8th Day | — |
Secondary
| Measure | Time frame |
|---|---|
| All cause mortalityTimepoint: 4th Day, 8th Day;Time to recovery from deliriumTimepoint: 4th Day, 8th Day | — |
Countries
India
Contacts
Public ContactPraveen Rikhari
Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Jollygrant, Dehradun
Outcome results
None listed