Health Condition 1: M150- Primary generalized (osteo)arthritis
Conditions
Interventions
Intervention1: Small molecule inhibitor gel: Topical application of the small molecule inhibitor gel on the patient diagnosed with OA knee for 6 weeks. Frequency - once daily
Control Intervention1: Di
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with OA knee, Age group between 40-85 years, Primary Osteoarthritis of at least one knee, and a flare of pain after withdrawal of prior therapy with either an oral NSAID or acetaminophen used at least 3 days per week during the previous month.
Exclusion criteria
Exclusion criteria: Secondary arthritis related to systemic inflammatory arthritis (including rheumatoid arthritis, psoriatic arthritis, post-infectious arthritis and metabolic arthritis, traumatic arthritis or surgical joint replacement), corticosteroid use, History of alcohol or drug abuse, Pregnant women and Lactating mothers, Concomitant skin disease at the application site.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| If the Small molecule inhibitor gel is found to be effective, it will help in improving the pain and stiffnessTimepoint: Pre intervention - Pain score is assessed at baseline Intervention - 6 weeks Post intervention - At the end of 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| If Small molecule inhibitor gel is found to be effective, will help in improving the regeneration of the cartilageTimepoint: Pre intervention - Pain score is assessed at baseline Intervention - 6 weeks Post intervention - At the end of 6 weeks | — |
Countries
India
Contacts
Public ContactDr Sree Aarthi D
Saveetha Medical College and Hospital
Outcome results
None listed