A scientific experiment comparing two drugs Fentanyl and Buprenorphine when used along with the drug Hyperbaric Levobupivacaine in patients coming for cesarean section.

The Efficacy of Fentanyl versus Buprenorphine as an adjuvant to intrathecal hyperbaric levobupivacaine in Cesarean section:A prospective Randomised comparative clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082275

Enrollment

Registered

2025-03-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fentanyl: Under aseptic precautions lumbar puncture done at L3-L4 level using 25G Quincke spinal needle, after getting free flow of CSF 1.8ml injection hyperbaric levobupivacaine 0.5% h

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age group 18 to 35 years, belonging to ASA grade 1 and 2 ,with height ranging from 150-180cms.,and weight ranging from 50-90kgs. coming for cesarean delivery.

Exclusion criteria

Exclusion criteria: .Patients with spinal deformity .Gestational age less than 36 weeks .Patients with medical and obstetric complication .Patients allergic to study drugs .Patients with local skin infections .Patients with impaired renal and liver function tests .Patients with coagulation disorder ,Patients not willing to give consent

Design outcomes

Primary

Measure	Time frame
.Onset and duration of sensory blockade .Maximum sensory blockade and time taken for it .Time for two segment sensory regression .Total duration of analgesia .Onset and duration of motor blockade .Quality of motor blockade and time taken for maximum motor blockade.Timepoint: .Time of onset of sensory block at T10 .Time of attaining maximum sensory blockade .Time for two segment sensory regression .Total duration of analgesia .Time taken for maximum motor blockade.	—

Measure

Time frame

.Onset and duration of sensory blockade .Maximum sensory blockade and time taken for it .Time for two segment sensory regression .Total duration of analgesia .Onset and duration of motor blockade .Quality of motor blockade and time taken for maximum motor blockade.Timepoint: .Time of onset of sensory block at T10 .Time of attaining maximum sensory blockade .Time for two segment sensory regression .Total duration of analgesia .Time taken for maximum motor blockade.

—

Secondary

Measure	Time frame
.Hemodynamic parameters like HR,SBP,DBP,MAP .Neonatal assessment using APGAR scoring .Adverse effectsTimepoint: 24hrs	—

Countries

India

Contacts

Public ContactNandakishor A Mane

MYSORE MEDICAL COLLEGE AND RESEARCH INSTITUTE

vijayanagaraj@yahoo.co.in9886239622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026