A Randomized controlled Trial of PGE2 gel versus Transcervical Foley Catheter for Induction of Labor in Women with Previous Cesarean Section

A Randomized controlled Trial of PGE2 gel vs Transcervical Foleys Catheter for Induction of Labor in Women with Previous Cesarean Section - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082243

Enrollment

Registered

2025-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery Health Condition 2: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Induction OF LABOUR by Foleys catheter: Induction of labor by Foleys catherter compared to Induction of labour by PGE 2 gel in Women with prevous 1 LSCS Control Intervention1: Inducti

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women with history of previous one Lower segment cesarean section with Singleton pregnancy Gestational age more than 34 weeks Cephalic presentation Bishop score of less than or equal to 6 Reactive Non stress test Patients willing for Vaginal delivery after previous one LSCS

Exclusion criteria

Exclusion criteria: Contraindication to use of prostaglandins like history of bronchial asthma Previous uterine surgery other than Lower segment cesarean section Placenta Previa Active genital tract infection Abnormal fetal heart rate pattern Allergy to latex Patient refusal for consent of induction or vaginal delivery Any other contraindication for TOLAC

Design outcomes

Primary

Measure	Time frame
To compare the change in Bishop score after 12 hours of induction with PGE 2 gel and transcervical Foley catheter in women with previous one LSCS. Timepoint: 2 years	—

Secondary

Measure	Time frame
To compare mode of delivery between PGE2 gel versus Foleys catheter used for induction of labor Timepoint: 2 years; To compare the rate of fetal distress between PGE2 gel versus transcervical Foley catheter for induction of labor in women with previous one LSCSTimepoint: 2 years; To compare induction to delivery interval between PGE 2 gel versus transcervical Foley catheterTimepoint: 2 years;To compare maternal complications like uterine tachysystole uterine rupture between PGE2 gel & Foley catheter useof labor in used for induction of labor in women with previous 1 LSCSTimepoint: 2 years;To compare APGAR score between PGE2 & Foley catheter used for induction of labor in women with previous 1 LSCSTimepoint: 2 years	—

Measure

Time frame

To compare mode of delivery between PGE2 gel versus Foleys catheter used for induction of labor Timepoint: 2 years; To compare the rate of fetal distress between PGE2 gel versus transcervical Foley catheter for induction of labor in women with previous one LSCSTimepoint: 2 years; To compare induction to delivery interval between PGE 2 gel versus transcervical Foley catheterTimepoint: 2 years;To compare maternal complications like uterine tachysystole uterine rupture between PGE2 gel & Foley catheter useof labor in used for induction of labor in women with previous 1 LSCSTimepoint: 2 years;To compare APGAR score between PGE2 & Foley catheter used for induction of labor in women with previous 1 LSCSTimepoint: 2 years

—

Countries

India

Contacts

Public ContactDr Priya

AIIMS JODHPUR

drmanu_8@yahoo.co.in9971833603

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026