Health Condition 1: A419- Sepsis, unspecified organism
Conditions
Interventions
Intervention1: Fluid Resuscitation: Surviving Sepsis Campaign (SSC) guidelines 2021 will be followed for guiding the treatment of septic shock including hemoglobin levels and mechanical ventilator set
Sponsors
Dr Ekta Tiwari
Eligibility
Inclusion criteria
Inclusion criteria: 1.All patients more than 18 years of age admitted in ICU with sepsis shock. 2.Patient presenting with septic shock. (According to sepsis-3 definition, Septic shock is defined as persistent hypotension despite adequate fluid resuscitation and need for vasopressor requirement to target mean arterial pressure (MAP) more than or equal to 65mmhg more than 2 mmol per L blood lactate levels and as per dynamic fluid resuscitation. 3.Patients in those central line can be inserted
Exclusion criteria
Exclusion criteria: 1.Age less than 18 years 2.Pregnancy & lactating women 3.Patient with congestive heart failure 4.Patient with active bleed 5.Patient refusing for consent for enrolment in the study 6.Inability to insert central insertion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the correlation between the three perfusion markers (lactate level, capillary refill time & P(c-va) co2 gradient) in hospitalTimepoint: 0, 3, 6, 12, 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| In hospital mortalityTimepoint: 30 days;Organ FailureTimepoint: 1st, 3rd day;Vasopressor dose & durationTimepoint: At discharge;Fluid requirementsTimepoint: 12hr, 24 hrs;Need of Invasive mechanical ventilation & duration of mechanical ventilation in days.Timepoint: At discharge;Need for RRT & number of days on RRT (Renal Replacement Therapy)Timepoint: At discharge;Cumulative fluid balanceTimepoint: Day1, Day3;ICU & Hospital Length of StayTimepoint: At discharge | — |
Countries
India
Contacts
Public ContactDr Sumit Ray
Holy Family Hospital
Outcome results
None listed