Comparison of Two dose 4mg and 8mg of dexamethasone in supraclavicular brachial plexus block with 0.5% bupivacaine in upper limb surgeries for onset duration and postop analgesia

Comparison of Dexamethasone 4 mg and 8 mg as an Adjuvant to 0.5% Bupivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgeries - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082208

Enrollment

Registered

2025-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone 8 mg with BUPIVACAINE 0.5% Plain 20 ml in supraclavicular brachial plexus block.: 20ml 0.5% Bupivacaine with 8 mg dexamethasone as adjuvant given as stat dose in supraclav

onset and Post operative pain relief in 24 hour. Control Intervention1: Dexamethasone 4 mg with BUPIVACAINE 0.5% Plain 20 ml in supraclavicular brachial plexus block.: 20ml 0.5% Bupivacaine with 4 mg

onset and Post operative pain relief in 24 hour.

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade : I,II,III 2. Elective upper limb surgeries under supraclavicular brachial plexus block. 3. Patient giving consent.

Exclusion criteria

Exclusion criteria: 1. Any bleeding disorder and patient on anticoagulants 2. Contralateral lung injury and rib fracture 3. Pre-existing neuropathy involving the surgical limb 4. Local infection at the injection site 5. History of allergy to local anaesthetic and dexamethasone 6. Patients with a history of peptic ulcer disease, hepatic or renal failure (contraindication to steroids) 7. Pregnant women 8. Systemic use of corticosteroids for 2 weeks or longer within 6 months of surgery 9. Unwilling patient

Design outcomes

Primary

Measure	Time frame
To compare duration and onset of sensory and motor blockage in both groupTimepoint: To compare duration and onset of sensory and motor blockage in both group starting from baseline to every 3 min with 3 point scale method.	—

Secondary

Measure	Time frame
To compare hemodynamic parameter intraoperative and To compare complication intraoperative and postoperative in both groupTimepoint: 24 hour postoperative	—

Countries

India

Contacts

Public ContactDr Ramila Jamaliya

B.J. Medical College and Civil Hospital , Ahmedabad

ramilajamliya@gmail.com9427702172

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026