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Comparative Study Of Two Types of Total Hip arthoplasty in Sickle Cell Disease

An open labelled randomised controlled study to compare the Functional and Radiological outcome of Cemented and uncemented Stem in Total Hip Arthroplasty for Avascular Necrosis of femoral head in patients of Sickle Cell disease - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082194
Enrollment
32
Registered
2025-03-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: M363- Arthropathy in other blood disorders Health Condition 3: M873- Other secondary osteonecrosis Health Condition 4: D571- Sickle-cell disease without crisis

Interventions

Intervention1: TOTAL HIP REPLACEMENT SURGERY: TOTAL HIP REPLACEMENT is done using uncemented Acetabular cup in all cases combined with Uncemented Femoral stems in patients with Avascular Necrosis of

Sponsors

All India Institute Of Medical Sciences Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.All patients of sickle cell disease 20-60 years with AVN femoral head in FICAT and ARLET Stage 3 and above who will require Primary Total Hip Arthroplasty 2.Patients with valid informed consent and medically fit to undergo surgical procedure

Exclusion criteria

Exclusion criteria: 1. Patients with AVN of aetiology other than Sickle cell disease 2. Age more than 60 years 3. Patient with High-risk behaviour such as chronic alcoholism and IV drug abuse. 4. Patients with Poor cognitive and neurological Function. 5. Patients who have sustained intraoperative Periprosthetic fractures which may hamper the implant stability and precludes immediate weight bearing. 6. Any deformity in the Femur and acetabulum requiring special consideration 7. All Revision Total Hip Arthroplasty

Design outcomes

Primary

MeasureTime frame
Primary aim of the study: To compare the Harris Hip score,Range of Motion,Incidence of loosening of components and Failure which requires further revision total hip arthoplasty .Timepoint: Follow up will be done at 6 week,6 months and 1 year.—

Secondary

MeasureTime frame
To assess Intraoperative - • Duration of surgical procedure • Blood Loss • Intraoperative complication Postoperative -• Length of Hospital stay • Limb Length Discrepancy • Greater trochanteric pain • Implant Position. • Thromboembolic ComplicationsTimepoint: 3 months and 6 month and 1 year follow-up—

Countries

India

Contacts

Public ContactSANTU SARKAR

AIIMS Raipur

dralokcagrawal@yahoo.co.in9425151634

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026