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Use of Curcumin and Resveratrol combination in addition to teeth cleaning to cure severe gum diseases

Clinical efficacy of combined Curcumin and Resveratrol oral in-situ gels as local therapeutics in the treatment of stage I and stage II Periodontitis - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082135
Enrollment
80
Registered
2025-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Curcumin longa is a rhizome which has been used since ages due to its anti-inflammatory, antimicrobial, anti-oxidant, antiseptic and anti-mutagenic effect.These properties help in reduc

Sponsors

Dr Boyapati Ramanarayana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with Stage I and Stage II Periodontitis. 2. Patients within the age group of 35 to 44 years of age for both genders. 3. Subjects with no history of allergies to the components used in the study 4. Patients with standard oral hygiene practices 5. Apparently healthy individuals

Exclusion criteria

Exclusion criteria: 1. Patients with habits like any form of tobacco, or alcohol consumption. 2. Systemically compromised patients 3. Pregnant women or lactating mothers 4. Patients who are on medication that influences periodontal health. 5. Patients with impacted teeth, non-functional teeth or prosthetic restorations 6. Patients who will not be able to be attend for follow up visits

Design outcomes

Primary

MeasureTime frame
1. Improvement in clinical attachment level 2.Reduction of Periodontal Pocket Probing DepthTimepoint: baseline,1 month,3 months

Secondary

MeasureTime frame
reduced inflammationTimepoint: baseline,1 month,3 months

Countries

India

Contacts

Public ContactDr Boyapati Ramanarayana

SIBAR INSTITUTE OF DENTAL SCIENCES

dr.ramanarayana@gmail.com9490144365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026