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This study tests three different ways to numb the pain in patients whose first pain relief shot didn t work during molar treatments. The goal is to find the best method to make the procedure pain-free.

Comparative evaluation of the Anesthetic efficacy of 4 Percent Articaine using 3 different supplemental injection techniques in Mandibular 1st Molar after failed Inferior Alveolar Nerve Block- A Randomised Clinical Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082128
Enrollment
60
Registered
2025-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Inferior Alveolar Nerve Block with 2 percent Lidocaine: Patient is first given IANB with 2 percent Lidocaine and the supplemental anesthesia with 4 percent Articaine using Buccal Infil

Sponsors

Sandhi Jaswal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient experiencing spontaneous and moderate to severe pain in mandibular 1st Molar diagnosed with symptomatic irreversible pulpitis 2. Patients in the age group of 18-60 years 3. Mature teeth with closed apex 4. Teeth with healthy periodontium

Exclusion criteria

Exclusion criteria: 1. Patients with History of significant medical conditions 2. Patient allergic to local anesthesia or sulfides 3. Pregnant women 4. Patients having active sites of pathosis in the area of injection 5. No bleeding after access opening 6. Teeth with periapical radiolucency 7. Patients who consumed medications like analgesics, narcotics, sedation, antianxiety or antidepressants before the treatment 8. Patients having any other region of active pain in the same quadrant along with mandibular 1st molar

Design outcomes

Primary

MeasureTime frame
Pain assessment will be conducted following the administration of a supplemental anesthetic injection after a failed inferior alveolar nerve block, during access opening, initial file placement and instrument the tooth using a 10-point pain intensity scale post-treatment.Timepoint: The Supplemental Injection will be given 15 minutes after the IANB.

Secondary

MeasureTime frame
NATimepoint: NA

Countries

India

Contacts

Public ContactSandhi Jaswal

Bhojia Dental College and Hospital

amitapsk2002@yahoo.com9878027370

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026