Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Butorphanol Nalbuphine and Levobupivacaine: Evaluation of intrathecal butorphanol and nalbuphine as an adjuvant to levobupivacaine in subarachanoid block: a comparative study
3 groups c
Sponsors
Department of Anaesthesiology School of Medical Sciences and Research, Sharda University
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient scheduled for surgery under subarachnoid block 2.Age 18-60 years 3. Both genders 4. ASA grade I and II
Exclusion criteria
Exclusion criteria: 1.ASA grade III and IV 2.Patient refusal to participate in study 3.Morbid obesity 4. Patient with history of adverse response to study drugs 5. Patient with pre-existing neurological or spinal disease, cardiovascular disease, renal, hepatic or any other systemic disease. 6. Pregnant females 7 Coagulopathy or bleeding diathesis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of intrathecal nalbuphine versus butorphanol as an adjuvant to 0.5% Levobupivacaine in subarachnoid block in respect to: 1. Time of onset and duration of sensory blockade assessed by pinprick and Visual Analog Score (VAS). 2. Time of onset and duration of motor blockade assessed by modified Bromage scale.Timepoint: Post operative period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Changes in vitals parameters- Heart rate (HR), Noninvasive Blood Pressure (NIBP) & Oxygen Saturation (SPO2). 2. Requirement of first analgesic rescue in postoperative period in the first 24 hours.Timepoint: Post operative period | — |
Countries
India
Contacts
Public ContactDr Manish Kumar Agarwal
School of Medical Sciences and Research Sharda University Greater Noida
Outcome results
None listed