Comparing effectiveness of two different materials on healing of infection in upper front teeth

Evaluation of Local Drug Delivery with Simvastatin incorporated hydrogel in treatment of periapical lesions: A Clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082098

Enrollment

Registered

2025-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Simvastatin hydrogel: Simvastatin hydrogel used as an intra canal medicament for treatment of periapical lesions in maxillary anterior region and evaluation after 1,3 and 6 months Contr

Eligibility

Inclusion criteria

Inclusion criteria: Patient presenting with chronic apical periodontitis in the Maxillary Anterior teeth with periapical lesions as seen on the radiograph Patient provides informed consent

Exclusion criteria

Exclusion criteria: Unwilling patients Patients with obstructed canals Smokers and alcoholics Pregnant and lactating women Periodontally compromised teeth Patients with bleeding disorders Patients who have an allergy to Simvastatin Patients on oral Simvastatin

Design outcomes

Primary

Measure	Time frame
Reduction in size of periapical lesion in maxillary anterior teeth after using simvastatin, calcium hydroxide as intra canal medicamentTimepoint: 1 month 3 months 6 months	—

Secondary

Measure	Time frame
Effectiveness of simvastatin hydrogel as an intra canal medicamentTimepoint: 1 month 3 months 6 months	—

Countries

India

Contacts

Public ContactGaurav Sharma

Army College of Dental Sciences

mamkaushik@gmail.com09535433129

Outcome results