Health Condition 1: F102- Alcohol dependence
Conditions
Interventions
Intervention1: High Amylose Maize Starch or HAMS: 95 grams daily for 6 weeks
Control Intervention1: Treatment as Usual: Dietary intake as usual
Sponsors
Dr Shree Mishra
Eligibility
Inclusion criteria
Inclusion criteria: Patient meeting criteria for Alcohol Dependence according to ICD 10 criteria. Patient with SADQ or Severity of Alcohol Dependence Questionnaire score greater than 16.
Exclusion criteria
Exclusion criteria: Patients body mass index or BMI greater than 30 kg per m2 Patients with diabetes Patients with chronic inflammatory disease such as rheumatoid arthritis, inflammatory bowel disease Patients with cancer Patients who took antibiotics, glucocorticoids, or nonsteroidal anti-inflammatory drug for 2 months preceding the enrolment Patient having overt liver disease, cirrhosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive Assessment according to Cambridge Neuropsychological Test Automated Battery or CANTAB Stool sample assessment for , short chain fatty acid, absolute and Relative abundance of bacterial speciesTimepoint: -3 day, 0 day, 30 days, 60 days, 90 days, 180 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Institute Withdrawal Assessment Alcohol -revised (CIWA-ar) score Obsessive Compulsive Drinking Scale (OCDS) score Barratt Impulsiveness Scale score Readiness to Change Questionnaire (RCQ) score Severity of Alcohol Dependence Questionnaire (SADQ) score Social Cognition Rating Tools in Indian Setting (SOCRATIS) score p300 Event related potential (ERP) Timepoint: -3 day, 0 day, 30 days, 60 days, 90 days, 180 days | — |
Countries
India
Contacts
Public ContactDr Shree Mishra
ALL INDIA INSTITUTE OF MEDICAL SCIENCES, BHUBANESWAR
Outcome results
None listed