Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: GLYCOPYRROLATE: A dose of 8 mg Intravenous in 100 ml is administered 2 hours before spinal anaesthesia .
Control Intervention1: DEXAMETHASONE: a single preoperative dose of DEX 8 mg int
Sponsors
ESIC MEDICAL COLLEGE HOSPITAL CHENNAI
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient with written informed consent. 2.ASA physical status I–II, adult. 3.Patients, of both genders, aged between 18 and 45 years. 4.Scheduled for elective non caeserean surgeries requiring spinal anaesthesia.
Exclusion criteria
Exclusion criteria: 1.Patient refusal. 2.Diabetics and pre-diabetes. 3.Aged more than 45 years or less than 18 years . 4.Patients with contraindications to SA (e.g., coagulopathy, thrombocytopenia, allergy to the local anaesthetic agent) and 5.Patients on steroids or serotonin-related medications (e.g., selective serotonin reuptake inhibitors) were ort. 6.Patients having glycopyrrolate contra-indications (glaucoma, hyperthyroid, morbid obesity, cardiovascular disease, pulmonary disease, renal or hepatic dysfunction, and neuromuscular disease)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ATTENTUATION OF FALL IN BLOOD PRESSURETimepoint: 0 minutes,1 minutes,3 minutes,5 minutes,10 minutes,20 minutes,30 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| anti secretary , antiemesisTimepoint: 0 minutes,1 minutes,3 minutes,5 minutes,10 minutes,20 minutes,30 minutes | — |
Countries
India
Contacts
Public ContactDR SATHYA NARAYANAN K
ESIC MEDICAL COLLEGE and HOSPITAL CHENNAI
Outcome results
None listed