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Transcranial direct current stimulation for cognitive improvement in Primary Open angle individuals.

TO EVALUATE EFFECTIVENESS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) FOR IMPROVING COGNITIVE FUNCTION IN PRIMARY OPEN ANGLE GLAUCOMA (POAG) - nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082070
Enrollment
30
Registered
2025-03-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H401- Open-angle glaucoma

Interventions

Intervention1: TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS): tDCS(trans cranial direct current stimulation ) - 2mA of current will be delivered to left dorsolateral prefrontal cortex (DLPFC) for 20

Sponsors

RAJENDRA PRASAD INSTITUTE OF OPHTHALMIC SCIENCES AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of POAG Age more than 40 years BCVA more than 6 by 12 in both eyes Literate, educated up to 5th standard Willing to participate in study

Exclusion criteria

Exclusion criteria: Patients with other forms of glaucoma Age less than 40 years BCVA less than 6 by 12 in either eye Eye disease other than glaucoma that could have affected RNFL and GC-IPL thickness, such as macular degeneration and optic neuropathy Patients on systemic medications which could affect cognition example BZPs, Opiates, TCAs, Anticonvulsants and Dopamine agonists. Patients with diagnosed neurological or psychiatric disease. Patients with chronic systemic disease such as Diabetes, Coronary Artery Disease or Cerebrovascular Disease

Design outcomes

Primary

MeasureTime frame
To evaluate the change in cognitive functioning after tDCS in individuals with Primary Open Angle Glaucoma (POAG)Timepoint: At baseline and follow up at 1 month and 3 month

Secondary

MeasureTime frame
To evaluate the association of cognitive functioning in POAG with Quality of life using EuroQol (EQ-5D-5L) To evaluate the association of cognitive functioning in POAG with Retinal nerve fiber layer (RNFL) and Ganglion cell layer (GCC) on Optical Coherence Tomography(OCT) Visual field sensitivity on Automated Perimetry Endogenous cortisol levels Timepoint: At baseline and follow up at 1 month and 3 month

Countries

India

Contacts

Public ContactDIKSHA SINGHAL

DR R.P CENTRE OF OPHTHALMIC SCIENCES NEW DELHI

tanujdada@gmail.com9873336315

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026