To find out effectiveness of co loading of same volume of crystalloid at 50ml/min and 100 ml/min to prevent spinal anaesthesia induced hypotension during elective cesarean section in 21-40 years old pregnant females at Maharaja Agrasen Medical College.

Comparison of co-loading of same volume of crystalloid at different rates to prevent spinal anaesthesia induced hypotension during cesarean section:A Randomised Controlled Trial - RCT

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082038

Enrollment

134

Registered

2025-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: To find out effectiveness of co loading of crystalloid at 50ml/min to prevent spinal anaesthesia induced hypotension during elective cesarean section.: To find out effectiveness of co l

Eligibility

Inclusion criteria

Inclusion criteria: 21-40 year old females, ASA Grade 2, undergoing elective or category 3/4 cesarean section giving consent to participate in study

Exclusion criteria

Exclusion criteria: 1.Pregnant females with coexisting co morbidity 2.Patients refusal to participate or not giving consent 3.Contraindication of spinal anaesthesia or any deviation in anaesthesia protocol 4.Pregnant females weighing less than 50kg and more than 100kg 5.Pregnant females with height less than 140cm and more than 160cm

Design outcomes

Primary

Measure	Time frame
1.Incidence of maternal hypotension (more than 20% fall in BP) 2.Number of vadopressordrug rescue boluses needed to treat hypotensionTimepoint: every minute for first 10 minutes and every 3 minutes there after till completion of surgical procedure	—

Secondary

Measure	Time frame
1.Incidence of complications(bradycardia,nausea,vomiting,light headedness) 2.Highest & lowest recorded blood pressure(%above & below baseline)Timepoint: every minute for first 10 minutes & every 3 minutes there after till completion of surgery	—

Countries

India

Contacts

Public ContactDr Komal

Maharaja Agrasen Medical College and Hospital,Agroha

docsanjeevparmar77@gmail.com8059598861

Outcome results