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A study to differentiate between scrub typhus and leptospirosis infections

A study to assess the disease severity among scrub typhus and leptospirosis patients using clinical, immunological, and molecular tools - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/03/082030
Enrollment
311
Registered
2025-03-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A270- Leptospirosis icterohemorrhagica Health Condition 2: A279- Leptospirosis, unspecified Health Condition 3: A753- Typhus fever due to Rickettsia tsutsugamushi

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

ICMR Small Extramural funding scheme
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with suspected or confirmed diagnosis of scrub typhus and leptospirosis. For healthy controls, participants with no history of fever for the past month

Exclusion criteria

Exclusion criteria: Pregnant women, Individuals with coinfections, immunocompromised, and autoimmune disorders

Design outcomes

Primary

MeasureTime frame
Understanding the predictors to distinguish between scrub typhus and leptospirosis based on clinical, laboratory, and immunological profileTimepoint: 2nd year—

Secondary

MeasureTime frame
Understanding the importance/role of corticosteroids in the management of severe scrub typhus patients Development and Standardization of Multiplex PCR for early detection of scrub typhusTimepoint: 3rd Year—

Countries

India

Contacts

Public ContactDr Kavitha Saravu

Kasturba Medical college Manipal

kavitha.saravu@manipal.edu9448107636

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026