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comparison between inhalational agents isoflurane and sevoflurane on blood glucose level and surgical stress response in patients posted for elective intracranial surgeries

Effect of intraoperative use of isoflurane and sevoflurane on blood glucose level in patients posted for elective intracranial surgeries: A randomized double blinded study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081996
Enrollment
102
Registered
2025-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C69-C72- Malignant neoplasms of eye, brain and other parts of central nervous system

Interventions

Intervention1: isoflurane: The amount of inhalational agent present in the alveoli after starting the procedure is to be noted every hour for a period of four hours intraoperatively to record the dept

Sponsors

Institute of medical sciences and SUM Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients posted for elective intracranial surgeries

Exclusion criteria

Exclusion criteria: diabetic, pregnant, comorbidities, thyroid dysfunction, renal disease, glucose metabolism disorder

Design outcomes

Primary

MeasureTime frame
difference in hourly intraoperative blood glucose levels in patients undergoing elective intracranial surgeries while using isoflurane compared to sevofluraneTimepoint: heart rate blood pressure mean arterial pressure surgical stress response to be measured at Baseline first hour second hour third hour fourth hour

Secondary

MeasureTime frame
attenuation of surgical stress response as measured by Surgical plethysmography indexTimepoint: 1 year

Countries

India

Contacts

Public ContactDr sumita swain

IMS and SUM Hospital

sumitabikash2015@gmail.com7978183938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026