To study the effects of gonadotropin with clomiphene citrate as compared to gonadotropin with letrozole in conception of infertile women.

A comparative study evaluating the efficacy of Gonadotropin in Conjunction with Clomiphene citrate versus Letrozole in Pregnancy rate in women with Ovulatory dysfunction undergoing intrauterine Insemination: A randomized control trial. - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081960

Enrollment

120

Registered

2025-03-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N970- Female infertility associated withanovulation

Interventions

Intervention1: Goup L :Gonadotropin with Letrozole: This group will receive Letrozole 2.5 mg BID for 5 days from day 2 of menstrual cycle.Later on HCG trigger will be given when follicle size becomes

Eligibility

Inclusion criteria

Inclusion criteria: Consenting women of Primary & Secondary infertility Polycystic ovarian syndrome Cervical factor infertility Retrograde ejaculation Patent fallopian tube, Mild male factor infertility

Exclusion criteria

Exclusion criteria: Women with Thyroid dysfunction, Hyperprolactinemia, Endometriosis. Uterine Pathology Tubal causes of Infertility

Design outcomes

Primary

Measure	Time frame
The Pregnancy Rate; Assessed: Chemically by a positive Beta HCG levels and Clinically by UltrasonographyTimepoint: Transvaginal USG will be done on days 3 9 12 of the cycle and then every 3 days	—

Secondary

Measure	Time frame
Endometrial Thickness Dominant Follicles Perifollicular blood flow Ovarian hyper stimulation syndromeTimepoint: TVS will be done on days 3 9 12 day of cycle and then every 3 days	—

Countries

India

Contacts

Public ContactDR KAMLESH CHAUDHARI

JNMC WARDHA(DMIHER)

dr.kamleshchaudhari@gmail.com9320568673

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026