Effect of Bone Graft with and without Spirulina Gel in Treating Bone Defect: A Clinical Trial

Comparative Evaluation of Demineralised Freeze-Dried Bone Allograft with and without Spirulina Gel in the treatment of Class II Furcation Defects: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081910

Enrollment

Registered

2025-03-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Spirulina gel with DFDBA: Stage III Periodontitis aged 30 to 60 patients exhibiting 25 Class Il furcation defects to be treated with spirulina gel with DFDBA Intervention Frequency -on

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients with stage III Periodontitis as assessed by Probing Pocket Depth (PPD) more than or equal to 6mm ,interdental clinical attachment level (CAL) more than or equal to 5 mm and Horizontal Probing Depth (HPD) more than or equal 2mm. 2) Bilateral buccal or lingual Class II furcation involvement

Exclusion criteria

Exclusion criteria: 1.Patients with history of systemic diseases, allergies or drug usage. 2.Patients who have undergone periodontal treatment in previous 6 months. 3.Pregnant and lactating females. 4.Smokers or tobacco chewers

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the effectiveness of DFDBA with and without Spirulina gel in the treatment of Class II Furcation defects clinically and radiographically by CBCT.Timepoint: at baseline,3 months and 6 months	—

Secondary

Measure	Time frame
1. Assess clinical parameters (CAL, PPD, HPD) in Class II furcation defects treated with Spirulina gel + DFDBA and DFDBA alone. 2. Evaluate radiographic bone fill using CBCT in defects treated with Spirulina gel + DFDBA and DFDBA alone. 3. Compare the clinical and radiographic outcomes between Spirulina gel + DFDBA and DFDBA alone over time.Timepoint: baseline, 3, and 6 months.	—

Countries

India

Contacts

Public ContactDr Dhawal Mody

Ranjeet Deshmukh Dental College and Research Center

periowell@gmail.com8055775977

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026