Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: Ultrasound guided high molecular weight hyaluronic acid injection for early stage knee osteoarthritis: Single dose injection of high molecular weight hyaluronic acid injection containi
Sponsors
Dr S Ravindran
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of primary knee osteoarthritis Kellgren-Lawrence grade less than 3
Exclusion criteria
Exclusion criteria: Age less than 50 years Kellgren-Lawrence more than or equal to 3 History or active presence of clinically significant inflammatory articular or rheumatic disease other than osteoarthritis Rapidly progressive osteoarthritis before the start of trial History of lower extremity surgery Excessive mechanical axis deviation varus more than 5 degree, valgus more than 5 degree Body mass index more than 30 History or presence of malignant disorders systemic disorders, such as diabetes mellitus, severe cardiovascular diseases, hematologic diseases, immune-deficiencies, and infections Systematic or intra-articular corticosteroid therapy in the previous 3 months Prior treatment with HA in the past 6 months Anticoagulants or antiaggregant therapy in the preceding 30 days Nonsteroidal anti inflammatory medications in the preceding 7 days Platelet count less than 150000 per mL Hemoglobin less than 12 gram per dL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The objective is to assess the change in Western Ontario McMaster Universities Osteoarthritis Index score which includes pain, stiffness and physical functionTimepoint: At 0, 1, and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr S Ravindran
Institute of Anaesthesiology, Government Rajaji Hospital & Madurai medical college, Madurai
Outcome results
None listed