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A study to assess the predictive value of simple blood count marker versus advanced cytokine biomarker for outcomes in off-pump coronary artery bypass surgery

A prospective observational study to assess the predictive value of simple blood count based marker versus advanced cytokine biomarker for outcomes in off-pump coronary artery bypass surgery - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/03/081887
Enrollment
80
Registered
2025-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I778- Other specified disorders of arteries and arterioles

Interventions

Intervention1: NIL: NIL Control Intervention1: advanced cytokine biomarker: To assess the predictive value of simple blood count based marker versus advanced cytokine biomarker for outcomes in off-pum

Sponsors

DR SARAH IQBAL
Lead Sponsor
Department of Anaesthesiology and Critical Care Jawaharlal Nehru Medical College AMU Aligarh
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective off pump Coronary Artery Bypass Grafting. Isolated CABG as per ESC/EACTS 2018 guidelines Age more than 18 years Either sex.

Exclusion criteria

Exclusion criteria: Patient refusal Patient undergoing repeat surgical procedures. Patients receiving steroid, NSAIDS, immunomodulatory therapy Patients having chronic HTN, chronic renal failure, serum ALT or AST level of twice the baseline value, active infection (preoperative total leukocyte count of more than 11.000/mm3) Those having history of recent CVA or MI (within 1 month) Severe LV dysfunction (LVEF less than 30%) Pre existing AF or utilizing antiarrhythmic therapy Preexisting neurological disease Patients of oncologic diseases

Design outcomes

Primary

MeasureTime frame
Acute Kidney Injury (AKI) in off-pump coronary artery bypass grafting Timepoint: 48 HOURS—

Secondary

MeasureTime frame
1- Atrial Fibrillation ( AF), and 3 Point Major Adverse Cardiovascular Events (3P-MACE) which includes coronary heart disease death, fatal or nonfatal ischemic stroke or myocardial infarction. 2- VIS Score 3- Total Mechanical ventilation time 4- Duration of ICU stay 5- 30- Day mortalityTimepoint: 30 days—

Countries

India

Contacts

Public ContactDR MANAZIR ATHAR

JAWAHARLAL NEHRU MEDICAL COLLEGE, Aligarh Muslim University

drmanazirathar@gmail.com8868056469

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026