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A study of systemic inflammatory indicators NLR, PLR, MLR, SII,SIRI and PIV as an early indicator for sepsis in PICU

ROLE OF SYSTEMIC INFLAMMATORY INDICES SUCH AS NLR, PLR, MLR, SII, SIRI AND PIV IN EARLY IDENTIFICATION SEPSIS IN PICU PATIENTS IN COASTAL DISTRICT OF DAKSHINA KANNADA- A PROSPECTIVE STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/03/081837
Enrollment
138
Registered
2025-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A418- Other specified sepsis

Interventions

Intervention1: Complete Blood Count: CBC reports of all the patients admitted to the PICU has been collected to calculate the Systemic Inflammatory Indices. No drugs, treatment or other tests were don

Sponsors

Kasturba Medical College, Mangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children fulfilling the criteria of sepsis and septic shock admitted to PICU according to the 3rd International Consensus Definition of 2016, during the study period

Exclusion criteria

Exclusion criteria: 1. Patients admitted with severe life-threatening complications other than sepsis. 2. Patients on long term medications including but not limited to antibiotics. 3. Not willing to participate.

Design outcomes

Primary

MeasureTime frame
The systemic inflammatory markers SIRI, SII, PIV, NLR, MLR, PLR can be used as an early indicator of Sepsis in PICUTimepoint: This decreases the need for waiting for the blood cultures for the diagnosis of sepsis and can help to decrease the turn over time significantly

Secondary

MeasureTime frame
Severity of sepsis to decide the mode of treatment and preferred antibioticsTimepoint: We aim to eliminate the time taken for cultures. With early treatment with antibiotics we can achieve better prognosis

Countries

India

Contacts

Public ContactSahajanya Srikanth

Kasturba Medical College, Mangalore

sahajanya.srikanth@learner.manipal.edu7022089289

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026