Health Condition 1: O141- Severe pre-eclampsia
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
ICMR
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria for mothers: All consenting primiparous mothers, 18-40yrs old diagnosed with preeclampsia according to ISSHP guidelines 2021, undergoing elective caesarean section between 37 weeks to 40 weeks of gestation in hospital will be included in the study. Inclusion Criteria for infant : All infants born to consenting primiparous mothers, 18-40yrs old diagnosed with preeclampsia according to ISSHP guidelines 2021, undergoing elective caesarean section between 37 weeks to 40 weeks of gestation in hospital will be included in the study.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for mother: Mothers not willing to give consent. Deliveries of unknown gestational age. Mothers with pre-existing chronic hypertension, chronic diabetes and other chronic illnesses. Exclusion Criteria for infant : Infants with obvious congenital anomalies. Infants suffering from meconium aspiration syndrome Infants with intrauterine growth restriction (IUGR) not related to pregnancy induced hypertension (PIH).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the effect of preeclampsia induced prenatal hypoxia on T Regulatory cell-related gene expression in the infant cord blood. Timepoint: Immediately at birth | — |
Secondary
| Measure | Time frame |
|---|---|
| To find a correlation between PO2, PCO2, lactate levels, bicarbonate levels & FOXP3, CTLA4 & GATA3 gene expression.Timepoint: Immediately at birth | — |
Countries
India
Contacts
Public ContactMallanagouda M Patil
Shri B M Patil Medical College Hospital and Research Centre
Outcome results
None listed