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Acute kidney Injury and its long term consequences in hospitalised patient

A Prospective Evaluation of long-term outcomes and survival after Acute Kidney Injury- the AKI-LOS study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/03/081780
Enrollment
640
Registered
2025-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N179- Acute kidney failure, unspecified

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients with AKI (Stage II and Stage III) who are 18 years of age or older (according to the KDIGO creatinine criteria from 2012) who are discharged alive after hospitalization for an acute/chronic illness will be included (irrespective of degree of recovery from AKI at discharge).

Exclusion criteria

Exclusion criteria: Patients with transient AKI (AKI that resolves within 48 hours of onset, as defined by KDIGO), known Chronic kidney disease (CKD) that already existed (or imaging suggestive of CKD), those with previous history of AKI (defined as one or more episodes of AKI known to have occurred in the past five years), those with acute glomerulonephritis, kidney transplant recipients and those who do not consent for participation and subsequent follow-up will be excluded.

Design outcomes

Primary

MeasureTime frame
New onset CKD is defined as (eGFR less than 60 mL/min/1.73 m2, as assessed by the CKD-EPI formula or a random urine protein to-creatinine ratio more than 150 mg/g.Timepoint: At baseline,12 months and 24 months

Secondary

MeasureTime frame
1. To analyse cardiovascular & all-cause mortality rates & risk factors among AKI survivors. 2. To assess the knowledge of AKI in survivors of an AKI episode using a validated questionnaire. 3. To explore AKI experience & potential barriers to post discharge AKI care in survivors of an AKI episode. 4. To study the incidence of new onset hypertension, recurrent AKI & hospitalizations in AKI survivors. Timepoint: Secondary objective 1:At baseline, 12 months & 24 months Secondary objective 2:At baseline, 6 months Secondary objective 3:At baseline, 6 months Secondary objective 4:At baseline, 12 months & 24 months

Countries

India

Contacts

Public ContactShayoli Sarkar

Kasturba Medical College, Manipal

indu.rao@manipal.edu9592896393

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026