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A study to examine and compare the effectiveness of using two different medications for reducing pain after breast cancer operation and also study the pain free time period after the injection.

A prospective randomised study comparing the efficacy of 0.25 % bupivacaine and 0.25% levobupivacaine in pectoral nerve type 2 block for postoperative pain relief in patients undergoing elective modified radical mastectomy - nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081759
Enrollment
70
Registered
2025-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Control Intervention1: Group 1: patients will recieve 0.25% bupivacaine after skin closure and efficacy of drug is assessed till 24hours after surgery Control Intervention2: Group 2: patients will rec

Sponsors

Department of anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients of ASA grade I and grade II patients between 18 to 65yrs

Exclusion criteria

Exclusion criteria: 1]patient refusal to the procedure 2]any contraindications for regional anaesthesia technique like infection at the site of injection 3]coagulation disorder 4]drug allergy 5]history of other cancer 6]history of previous breast surgery 7]ASA grade IV 8]respiratory disease, cardiac disease and renal disease 9]having chemotherapy or radiotherapy in recent 8 weeks

Design outcomes

Primary

MeasureTime frame
comparing the efficacy of 0.25% bupivacaine and 0.25% levobupivacaine in Carcinoma breast surgeries using PEC 2 block and the duration of postoperative analgesiaTimepoint: 24 hours

Secondary

MeasureTime frame
total rescue analgesia required in the first 24hrsTimepoint: 24hrs

Countries

India

Contacts

Public ContactDR DEEPA KATTISHETTAR

Mysore medical college and research institute

deepapalax@gmail.com9611104343

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026