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Effectiveness of cognitive control training in improving mental function among patients with major depression.

Efficacy of cognitive control training on alleviating cognitive deficits in individuals with MDD - Nil

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081747
Enrollment
132
Registered
2025-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F331- Major depressive disorder, recurrent, moderate

Interventions

Intervention1: Cognitive Control Training: The Cognitive Control Training (CCT) intervention will be conducted over a period of 8 weeks, consisting of 16 structured sessions, with a frequency of two s

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A diagnosis of depression according to ICD-11 criteria. Patients with MADRS score ranging between 7 and 34 will be included. Patients who can speak English, Hindi and Odia. Patients should have completed formal education up to at least the 10th-grade level. Patients from ages 18-60 years will be included in the study.

Exclusion criteria

Exclusion criteria: Patients with severe suicidal ideations will be excluded. Patients who have missed scheduled appointments for the therapy sessions. The presence of co-morbid mental health disorders (Bipolar disorders, Schizophrenia, substance use, personality disorder) will be excluded to maintain homogeneity in the study sample. Organic mental disorders Patients who are receiving antipsychotics, sedatives, and benzodiazepines will be excluded Unwillingness or inability to provide informed consent. Excluding major physical and surgical neurological conditions. Anyone with structured therapy will be excluded.

Design outcomes

Primary

MeasureTime frame
The study aims to assess the efficacy of Cognitive Control Training (CCT) on working memory and its impact on performance in the Wisconsin Card Sorting Test (WCST) and Stroop Test over an 8-week period.Timepoint: 8WEEKS

Secondary

MeasureTime frame
The study aims to assess the efficacy of Cognitive Control Training (CCT) on attention & its impact on performance in the Wisconsin Card Sorting Test (WCST) & Stroop Test over an 8 week period. It also aims to evaluate the efficacy of CCT on response inhibition & its effect on WCST & Stroop Test scores over the same duration. Additionally, the study will assess changes in Montgomery- sberg Depression Rating Scale (MADRS) scores in relation to improvements in cognitive deficits.Timepoint: 8 WEEKS

Countries

India

Contacts

Public ContactAshwini Rajmohan

Kalinga Institute of Medical Sciences

sayali.mishra@kims.ac.in7873383039

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026