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Comparison of Dexmedetomidine and Dexmedetomidine-Ketamine combination efficacy as intranasal premedication in paediatric infraumbilical surgeries

Comparison between effectiveness of Dexmedetomidine and Dexmedetomidine-ketamine combination as an intranasal premedication in paediatric infraumbilical surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081696
Enrollment
144
Registered
2025-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Control Intervention1: Intranasal dexmedetomidine-ketamine combination: Effectiveness of intranasal premedication with dexmedetomidine-ketamine combination is compared with intranasal dexmedetomidine

Sponsors

Dr Fehima Haris
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Paediatric patients of age 1-6 years of either sex undergoing elective infraumbilical surgeries of ASA physical status I or II

Exclusion criteria

Exclusion criteria: Known allergy to study drugs Cardiac arrhythmia or congenital heart disease Raised intracranial tension Children with mental retardation Intranasal mass or nasal bleeding

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness of intranasal dexmedetomidine versus intranasal dexmedetomidine-ketamine combination as a premedication in terms of mask acceptance score in paediatric patients undergoing general anaesthesia for infraumbilical surgeriesTimepoint: Mask acceptance score will be assessed at the time of induction that is 30 minutes after giving premedication

Secondary

MeasureTime frame
To assess level of sedation using Ramsay sedation score To determine Child-parent separation scoreTimepoint: Sedation assessed 15 & 30 minutes after premedication Child- parent separation score assessed at the time of parental separation or 30 minutes after premedication

Countries

India

Contacts

Public ContactDr Mumthas M S

Government medical college Kozhikode

suvarnakaniyil@gmail.com9447638221

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026