Comparing two methods of Lignocaine administration on airway and hemodynamic response during extubation following general anaesthesia.

Comparison of Madgic Device for 4 percentage Lignocaine administation with intracuff administration of 4 percentage Lignocaine on airway and haemodynamic response during emergence and extubation following general anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081659

Enrollment

Registered

2025-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 4% Lignocaine administration with Madgic device: 120mg Lignocaine administered peritubally with the atomizer (madgic device) Control Intervention1: Intracuff 4% Lignocaine administratio

Eligibility

Inclusion criteria

Inclusion criteria: American Society of anaesthesiologists physical status 1 2 Patients undergoing elective surgeries under general anaesthesia Surgery duration less than 2 hours

Exclusion criteria

Exclusion criteria: Patient refusal Patients with coagulation abnormalities Patients with neurological deficits Patients with cardivascular deficits Allergies to study medications Surgery duration more than 2 hours

Design outcomes

Primary

Measure	Time frame
To compare peritubal 4 percentage Lignocaine administration by Madgic device with intracuff administration of Lignocaine on haemodynamic response like systolic blood pressure, diastolic blood pressure, heart rate during extubation.Timepoint: To compare peritubal 4 percentage Lignocaine administration by Madgic device with intracuff administration of Lignocaine on haemodynamic response preextubation, 1minutes after extubation, 5minutes after extubation and 10minutes after extubation.	—

Measure

Time frame

To compare peritubal 4 percentage Lignocaine administration by Madgic device with intracuff administration of Lignocaine on haemodynamic response like systolic blood pressure, diastolic blood pressure, heart rate during extubation.Timepoint: To compare peritubal 4 percentage Lignocaine administration by Madgic device with intracuff administration of Lignocaine on haemodynamic response preextubation, 1minutes after extubation, 5minutes after extubation and 10minutes after extubation.

—

Secondary

Measure	Time frame
Incidence of cough and sore throat post extubationTimepoint: 5min after extubation	—

Countries

India

Contacts

Public ContactDr Kamodula Hema

KLE Dr Prabhakar Kore Hospital and MRC

dr.raghavendra.kalal@gmail.com9880712568

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026