A study to evaluate post operative pain relief in renal transplant recipient patients

A RANDOMIZED CONTROL STUDY TO EVALUATE THE EFFICACY OF INTRAOPERATIVE LIGNOCAINE INFUSION FOR POST-OPERATIVE PAIN RELIEF IN RENAL TRANSPLANT RECIPIENT PATIENTS. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081658

Enrollment

Registered

2025-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease Health Condition 2: N186- End stage renal disease

Interventions

Intervention1: Intravenous lignocaine: Intravenous lignocaine infusion at the rate of 1.5mg/kg/hour from induction to skin closure Control Intervention1: Normal saline 0.9%: Intravenous normal saline

Eligibility

Inclusion criteria

Inclusion criteria: 1. End stage renal disease patients undergoing recipient of elective live renal transplant surgery 2. Ages 18-65 3. Genders - male and female 4. ASA 2 and ASA 3 patients

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Allergic to lignocaine 3. Age less than 18 and more than 65 4. ASA 4 patients 5. Patients undergoing cadaver in renal transplants 6. Uncontrolled Hypertension and Diabetes Mellitus 7. Deranged liver function tests 8. NYHA III and IV 9. History of convulsions

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of intravenous lignocaine at 1.5 mg/kg/hr. in giving adequate post-operative pain relief in renal transplant patients by a combination of numeric pain scale and postoperative fentanyl consumption in comparison to the control group.Timepoint: Intra operative surgery time and the duration of patient controlled analgesia.	—

Secondary

Measure	Time frame
Intra operative hemodynamics, post operative nausea vomiting and recovery.Timepoint: Post operative recovery time.	—

Countries

India

Contacts

Public ContactSangeetha A

Manipal hospitals

jalaja1975@gmail.com9786031501

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026