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Clinical study to evaluate the use of injectable platelet rich fibrin for increasing soft tissue around dental implants

In-vitro & biomarker based clinical evaluation of I-PRF in soft tissue augmentation around dental implants - A single blinded randomized controlled trial. - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081649
Enrollment
66
Registered
2025-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: With Collagen and i-PRF: 33 implant sites treated with i-PRF infused collagen matrix during implant placement and evaluating the change in soft tissue width will be measured at 0,3 an

Sponsors

Dr P Harinath
Lead Sponsor
SRM Dental College
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients within the age range of 30-60 years. 2.Patients with thin soft tissue biotype. 3.Patient with single isolated edentulous sites requiring implant placement

Exclusion criteria

Exclusion criteria: 1.Patients requiring regeneration at the edentulous site. 2.Smoking(more than 10 cigs/day). 3. Pregnant and lactating women. 4. Patients showing unacceptable oral hygiene compliance during/after phase I therapy. 5. Systemic condition / disease/ any medication having influence on course of therapy 6. Patients with relative/absolute contraindication for implant placement.

Design outcomes

Primary

MeasureTime frame
To compare and evaluate changes in the buccal soft tissue thicknessTimepoint: Subject will be evaluated at 0,3 and 6 month

Secondary

MeasureTime frame
1.Changes in the width of the keratinized tissue 2.changes in the height in the gingival margin 3.Radiographic changes in the crestal bone 4.changes in the thickness of buccal bone 5.bleeding on probingTimepoint: Subject will be evaluated at 0,3 & 6 months

Countries

India

Contacts

Public ContactDr Nirmala Anandan

SRM Dental College

dr_s_nirmala@yahoo.com9444280636

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026