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Comparison Between Metaprolol and clonidine in fess surgery for Hypotensive Anaethesia

Comparative evaluation of oral metaprolol vs oral clonidine as premedication in induced controlled hypotensive anaesthesia for patients undergoing functional endoscopic sinus surgery under general anaesthesia - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081643
Enrollment
52
Registered
2025-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Drug (Clonidine- 2mcg/kg, Metaprolol-50mg): clonidine 2mcg/kg given Orally to one group of patients 1 hour before surgery and Metaprolol 50mg given Orally to one Group 1 hour before S

Sponsors

Dr Kalpana devi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to ASA I & II. Patients between ages 16 to 60. Patients undergoing FESS procedure.

Exclusion criteria

Exclusion criteria: Hypertensive patients. Patients who are not willing to participate in the study

Design outcomes

Primary

MeasureTime frame
Metaprolol gives a favourable profile when compare to clonidineTimepoint: 4 weeks

Secondary

MeasureTime frame
Metaprolol gives a favourable profile when compare to clonidineTimepoint: 4 Weeks

Countries

India

Contacts

Public ContactDr Kalpana devi

Esic medical College and hospital Chennai

gilang@rediffmail.com9884149429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026