Comparison of blood smear technique using Hemoglide tool with conventional method

Hemoglide- Advanced blood smear and transport technology: A point of care haematology tool - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081632

Enrollment

3000

Registered

2025-03-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R718- Other abnormality of red blood cells

Interventions

Intervention1: Staining and analysis: 1)Stain both the Hemoglide-prepared and manually prepared slides using standard staining protocols. 2)Analyze the stained slides under a microscope to assess: a

Eligibility

Inclusion criteria

Inclusion criteria: - Whole blood samples collected in EDTA anticoagulant tubes. - Samples from patients across all age groups and genders with clinical indications such as anemia, infection, leukemia, or other haematological conditions.

Exclusion criteria

Exclusion criteria: - Hemolyzed samples - Clotted samples - Samples with insufficient volume - Samples collected in incorrect anticoagulant

Design outcomes

Secondary

Measure	Time frame
To compare the accuracy of peripheral blood smear preparation between Hemoglide & conventional slide prepationTimepoint: After smear preparation & staining (within 1 hour), & after review by a blinded pathologist (within 24 hours);To compare the parameters like quality of smear (uniformity, distribution, absence of artifacts), staining quality, cell morphology clarity & smear preparation time.Timepoint: Smear preparation time: Measured at the time of smear preparation. Smear quality parameters: Evaluated immediately after staining & drying (within 1 hour). Blinded assessment by pathologists: Within 24 hours.;To compare the diagnostic turnaround time between Hemoglide & conventional slide prepationTimepoint: From the time of blood sample collection to the final pathologist report, recorded for each method (Hemoglide vs. conventional)	—

Measure

Time frame

To compare the accuracy of peripheral blood smear preparation between Hemoglide & conventional slide prepationTimepoint: After smear preparation & staining (within 1 hour), & after review by a blinded pathologist (within 24 hours);To compare the parameters like quality of smear (uniformity, distribution, absence of artifacts), staining quality, cell morphology clarity & smear preparation time.Timepoint: Smear preparation time: Measured at the time of smear preparation. Smear quality parameters: Evaluated immediately after staining & drying (within 1 hour). Blinded assessment by pathologists: Within 24 hours.;To compare the diagnostic turnaround time between Hemoglide & conventional slide prepationTimepoint: From the time of blood sample collection to the final pathologist report, recorded for each method (Hemoglide vs. conventional)

—

Primary

Measure	Time frame
To evaluate the effectiveness of Hemoglide, an advanced blood smear and transport technology, in improving the quality and efficiency of peripheral blood smear preparationTimepoint: Immediately after smear preparation and staining (within 1 hour of sample collection).	—

Countries

India

Contacts

Public ContactLalithaa J

Saveetha Medical College and Hospital

rpsmcchni@gmail.com9361209102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026