None listed
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Bill and Melinda Gates Foundation, USA
Eligibility
Inclusion criteria
Inclusion criteria: Healthy volunteers willing to participate in a longitudinal serosurvey among 1080 rural and 1080 urban participants to estimate the seroincidence of Vibrio cholerae in the community. All individuals above the age of 15 years from ~20,000 families in urban areas and all families from rural areas (three or four villages of Kaniyambadi block bordering Jawadhi hills) where wastewater surveillance is implemented for estimating the burden of pulmonary tuberculosis and drug-resistant tuberculosis.
Exclusion criteria
Exclusion criteria: If the participants is not willing to participate in the study. Refuse to provide consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rates of Salmonella typhi - Waste water surveillance.Timepoint: Fortnightly - two months from 54 urban sites followed by 20 urban sites for 30 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection rates of avian influenza virus - Waste water & samples from poultry markets.Timepoint: Fortnightly - 50 sampling location including 25 waste water sampling locations and 25 from poultry markets (20 urban & five rural areas in each) for 32 months;Detection rates of Vibrio cholerae - Waste water surveillance.Timepoint: Fortnightly - 25 waste water sampling locations (20 urban & five rural) for 32 months;Seroincidence for cholera - Dried blood spots.Timepoint: 3 time points; baseline, 4-6 months, 10-12 months. Cohort of 1080 participants from rural and urban area;Detection rates of MTBC, and TB AMR genes - Waste water surveillance.Timepoint: Fortnightly - 25 waste water sampling locations (20 urban & five rural) for 32 months;Prevalence of PTB, MDR-TB, and XDR TB in the community - Symptom screening & Sputum testing.Timepoint: Individuals above 15 years from ~20,000 families from urban areas and all families in the rural villages. All individuals screened positive for their symptom will be sputum tested | — |
Countries
India
Contacts
Public ContactVenkata Raghava Mohan
Christian Medical College
Outcome results
None listed