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To compare efficacy of dexmedetomidine and paracetamol for management of pain in laproscopic cholecystectomy

Comparative evaluation of dexmedetomidine and paracetamol on postoperative analgesia,perioperative hemodynamics and sedation for patients undergoing laproscopic cholecystectomy - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081627
Enrollment
80
Registered
2025-03-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Patients receiving intravenous dexmedetomidine: we will give intravenous dexmedetomidine 1mcg/kg as loading dose after induction of anaesthesia over 10 minutes followed by o.5mcg/kg/hr

Sponsors

Guru Nanak Dev Hospital Amritsar
Lead Sponsor
Dr Rajan Kumar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18-55 years if either sex undergoing laproscopic cholecystectomy American society of Anaesthesiologists grade 1 and 2 Duration of surgery less than 2 hours

Exclusion criteria

Exclusion criteria: Patients giving refusal for written consent Patients with known hypersensitivity to paracetamol or dexmedetomidine Hyperactive airway disorder Opioid or alcohol addiction Patients taking NSAIDS or any other analgesics Pregnant and morbidly obese patients Neurological and psychiatric disorder Coagulation disorder Renal and hepatic insufficiency Patients with chronic pain

Design outcomes

Primary

MeasureTime frame
Postoperative analgesia by numerical rating scale Sedation scoreTimepoint: time from the start of loading dose of dexmedetomidine or paracetamol given till 24 hours after surgery

Secondary

MeasureTime frame
Intraoperative and postoperative hemodynamics Post operative nausea and vomiting Rescue analgesiaTimepoint: time from the start of loading dose of dexmedetomidine or paracetamol given till 24 hours after surgery

Countries

India

Contacts

Public ContactDr Anu Sharma

Government medical college,Amritsar

anu.anaesthesia.97@gmail.com9814185884

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026