Efficacy of intravenous tranexamic acid in reducing p blood loss in abdominal hysterectomy surgery

Efficacy of intravenous tranexamic acid in reducing perioperative blood loss in abdominal hysterectomy- A double blinded randomized controlled trial - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081587

Enrollment

Registered

2025-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified

Interventions

Intervention1: tranexamic acid injection: 1gram of tranexamic acid 5 minutes before skin incision. it is an antifibrinolytic agent used to reduce blood loss Total duration: 5 minutes before skin incis

Eligibility

Inclusion criteria

Inclusion criteria: Women undergoing total abdominasl hysterectomy with or without bilateral salpingo-oophorectomy due to myoma, menorrhagia, abnormal uterine bleeding, fibroid, adenomyosis

Exclusion criteria

Exclusion criteria: patients with cardiac, renal, thromboembolic disease, adnexal mass and malignancy, pre existing anemia, allergy to tranexamic acid, anti coagulant therapy

Design outcomes

Primary

Measure	Time frame
estimated blood loss by weight, estimated blood loss by suction drainTimepoint: during ot, just postop, upto 24 hours postop	—

Secondary

Measure	Time frame
use of topical hemostatics, blood transfusion, drop in hb levelTimepoint: during ot, post-operative upto 24 hours postop	—

Countries

India

Contacts

Public Contactsatabdi bhattacharjee

Tezpur medical college and hospital

radharashmi2014@rediffmail.com9864013158

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026