Health Condition 1: 4- Measurement and Monitoring
Conditions
Interventions
Intervention1: A comparative efficacy between Sugammadex and Neostigmine plus Glycopyrronium bromide for the reversal of Vecuronium induced Neuromuscular blockade: A randomized controlled trial.: Grou
Sponsors
CHRISTIAN MEDICAL COLLEGE A ND HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA (American Society of Anaesthesiologists) I and II 2.All men and women. 3.Adult 18-60 years. 4.Elective General surgeries, Orthopedic, Laproscopic, Gynecological surgeries under general anaesthesia lasting for 2-3 hours. 5.Planned use of neuromuscular blocking drugs. 6.Planned endotracheal intubation and extubation in operating room.
Exclusion criteria
Exclusion criteria: 1.Anticipation of difficult airway. 2.Known or suspected neuromuscular disorder impairing neuromuscular function. 3.Allergy to muscle relaxants. 4.A personal or family history of malignant hyperthermia. 5.Pregnant females, breast feeding mothers, or females in childbearing age using contraceptives. 6.Renal impaired patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare the efficacy between Sugammadex and Neostigmine plus Glycopyrronium bromide to time of recovery of TOF ratio to 0.9.Timepoint: Under minimal block, time taken for extubation is recorded at intervals of 5 mins, 10mins,15mins and so on. | — |
Secondary
| Measure | Time frame |
|---|---|
| Post reversal physiological characteristics- Blood pressure, Heart rate, Spo2, Respiratory rate.Timepoint: At the interval of 0mins, 10mins, 20mins, 30mins, 60mins, 120mins | — |
Countries
India
Contacts
Public ContactDR SHEBA RATNA KUMARI KODALI
CHRISTIAN MEDICAL COLLEGE AND HOSPITAL
Outcome results
None listed