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Comparision of effect of two additives used along with local anesthetic agent in spinal anaesthesia in patients undergoing lower limb orthopedic surgeries

Comparision of Dexmedetomidine and Clonidine as an adjuvant to intrathecal hyperbarik bupivacaine in patients undergoing lower limb orthopedic surgery: A prospective double blind randomised controlled trial. - nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/081568
Enrollment
60
Registered
2025-03-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Bupivacaine with Clonidine or Bupivacaine with Dexmedetomidine: GROUP BC + BD : Patients will be administered alternatively with 0.5% Bupivacaine 2.8 ml +Clonidine 30mcg and 0.5% Bupiva

Sponsors

SDM College of Medical Sciences Dharwad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing surgical procedure for orthopedic lower limb injuries 2. Body mass index less than 30 kg per meter square 3. ASA grade 1 and 2

Exclusion criteria

Exclusion criteria: 1 Patients with bronchial asthma, neurologic condition and psychiatric disorder 2. Patients who are on beta blocker therapy or clonidine therapy 3 any contraindications to subarachniod block

Design outcomes

Primary

MeasureTime frame
Duration of post operative analgesiaTimepoint: Time point A: time from study drug injected Time point B : request for first rescue analgesic post operatively

Secondary

MeasureTime frame
Post operative visual analogies scoreTimepoint: Time point A: time from study drug injected Time Pont C : Visual Analogue score more than 4/10 post opratively;Adverse effectsTimepoint: Time point A: time from study drug injection Time point D: 24 hours from time point A

Countries

India

Contacts

Public ContactDr RAVI BHAT

SDM COLLEGE OF MEDICAL SCIENCES AND HOSPITAL, DHARWAD

kakkodravi@gmail.com9482181582

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026