Health Condition 1: B95-B97- Bacterial and viral infectious agents
Conditions
Interventions
Intervention1: The intervention involves developing, implementing, and evaluating a tailored antimicrobial stewardship (AMS) program in secondary care hospitals in India through a phased approach of s
Sponsors
Centre for Toxicovigilance and Drug Safety
Eligibility
Inclusion criteria
Inclusion criteria: Phase 1 Identification and selection of secondary care hospitals i. Hospitals having bed capacity typically ranging from 50-500 beds, and willing to participate in the study and collaborate with the research team ii. Hospitals located within the district to ensure accessibility for site visits and ongoing support iii. Hospitals having basic infrastructure and resources to support data collection and without a pre-existing AMS program iv. Availability of key stakeholders (e.g., hospital administration, medical staff) who are willing to engage in the study and provide necessary information v. Hospitals that agree to participate in the study following ethical approval from relevant ethics committees or institutional review board Point Prevalence survey i. Patients more than 18 years of age admitted in the clinical settings before 8 am on the study day ii. Patients prescribed with at least one systemic/oral antibiotic Phase 2 Qualitative Interview with the physician i. Physicians who are currently practicing in the selected clinical settings with more than 3 years of experience ii. Physicians with consent to participate in the study and willing to share their experiences and perspectives iii. Physicians available for the duration of the study and able to commit the necessary time for the interview
Exclusion criteria
Exclusion criteria: Phase 1 Identification and selection of secondary care hospitals i. Hospitals that do not consent to participate or show lack of interest in the study ii. Hospitals with fewer than 50 beds or more than 500 beds, thus not fitting the secondary care designation based on bed capacity iii. Hospitals with a well-established AMS program that do not require support or improvement in this area Point Prevalence survey i. Patients admitted after 8 am in the morning on data collection day ii. Patient in outpatient and emergency departments iii. Patients intended to be discharged on the day of survey iv. Patients posted for surgery on the day of the survey Phase 2 Qualitative interview with the physicians i. Physicians with fewer than the required minimum years of clinical practice (less than 3 years) ii. Physicians who do not consent to participate in the study or are unwilling to share their experiences and perspectives iii. Physicians who cannot commit the necessary time for the interview and any follow-up due to their schedule
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in inappropriate antimicrobial use, measured by compliance with Antimicrobial Stewardship (AMS) program recommendations and hospital-specific prescribing guidelines.Timepoint: Baseline, mid-implementation (4 months), and end of follow-up (8 months). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Percentage adherence to local antibiotic prescribing guidelines. 2. Improvement in AMS knowledge scores from pre-training to post-training. 3. Proportion of prescriptions identified as inappropriate based on AMS criteria. 4. Changes in healthcare-associated infection rates.Timepoint: Assessed at baseline and at the end of the follow-up period (8 months). | — |
Countries
India
Contacts
Public ContactDr Girish Thunga
Manipal College of Pharmaceutical Sciences
Outcome results
None listed