To Compare effects of injection Levobupivacaine with injection Ropivacaine in Breast Cancer Surgery

Study to Compare Effects of isobaric Levobupivacaine with isobaric Ropivacaine in Segmental Spinal in Patients posted for Modified Radical Mastectomy - Nill

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/081514

Enrollment

Registered

2025-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C504- Malignant neoplasm of upper-outerquadrant of breast

Interventions

Intervention1: Isobaric Levobupivacaine: 1.0ml (5mg) of isobaric levobupivacaine 0.5% and 5 mcg dexmedetomidine at T5-T6 intrathecal once at the time of induction Control Intervention1: isobaric Ropiv

Eligibility

Inclusion criteria

Inclusion criteria: 1 ASA I to III 2 Primary Brest cancer without known extension beyond Breast and Axillary nodes 3 scheduled for unilateral Mastectomy with or without Axillary neck dissection

Exclusion criteria

Exclusion criteria: 1 Inflammatory Breast Cancer 2 Previous Surgery for Breast Cancer 3 BMI more than 35kg per meter square 4 Uncontrolled Diabetes and Hypertension 5 Chronic Renal Disease

Design outcomes

Primary

Measure	Time frame
Hemodynamic stability Timepoint: baseline, 6 hours and 12 hours	—

Secondary

Measure	Time frame
Rescue AnalgesiaTimepoint: 12 hours and 24 hours	—

Countries

India

Contacts

Public ContactDr Anil Kumar

Government Medical College Jalaun(Orai)

dranilkumarucr@gmail.com09454224498

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026