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Comparing Bolus vs Fractionated Dose Spinal Anesthesia for Lower Limb Surgery

A prospective study to compare the efficacy of bolus dose versus fractionated dose injection of hyperbaric bupivacaine with dexmedetomidine in spinal anaesthesia among adult patients undergoing lower limb surgery - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081468
Enrollment
60
Registered
2025-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: single bolus dose of 3.8ml Of spinal drug.: Patients will be positioned in the sitting position. Painting of patients back will be done with povidone iodine solution followed by draping

Sponsors

Smt Bhikiben Kanjibhai Shah Medical Institute and Research Cen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing to sign the written informed consent. Patients belonging to American Society of Anaesthesiologists (ASA) Grade I or II. •Male or female patients between age range of 18- 60 years. Patients undergoing elective lower limb surgeries under spinal anaesthesia

Exclusion criteria

Exclusion criteria: •Patients unwilling to participate in the study. •Patient having arryhthmia or heart block. •Patients with renal, hepatic, cardiovascular and respiratory diseases. •Patients belonging to ASA Grade III or more. •Pregnant or lactating women. •History of known allergy to study drug. •Patients who needs supplementation of general anaesthesia. •Any contraindication to spinal anaesthesia (local site infection , coagulation disorder, raised intracranial pressure , hemodynamic instability, neurological disorders).

Design outcomes

Primary

MeasureTime frame
The study will help us to know which group provides longer duration of sensory and motor blockade and also which provides better hemodynamic stabilityTimepoint: sensory and motor block will be assessed every 2 minutes interval and onset of sensory and motor blockade will be noted and highest level of sensory block will be assessed sensory will be assessed every 30 min till regression to L1 motor blockade will be assessed till modified bromage score is 0 HR,SBP,DBP,MAP,SPO2 will be assessed at 0 min,3 min, 5 min, 10 min, 15 min, 30 min, 45min,60min,75min,90min, 120min, 150min, 180min

Secondary

MeasureTime frame
which method of spinal anaesthesia,will provide longer post operative analgesia in patient undergoing lower limb surgeryTimepoint: VAS SCORE:- 0,60,90,120,180 min

Countries

India

Contacts

Public ContactDr SARA MARY THOMAS

Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre

sara.cinosh@gmail.com9646500158

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026