Comparison of the Antimicrobial charecteristic of Orthodontic bands cemented with Glass Ionomer Cement (GIC) modified using Chitosan (CH) and Chlorhexidine (CLX): A patient based study

An evaluation and comparison of microbial colonization property of Orthodontic bands luted with Chitosan CH and Chlorhexidine CLX modified Glass Ionomer Cement GIC: An In Vivo Study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081448

Enrollment

Registered

2025-02-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: GIC modified with Chitosan Nanoparticle Liquid: 20 milligrams of Chitosan (CH) in powder form will be taken which will be combined with 1.8 milliliters of glacial acetic acid, completed

Eligibility

Inclusion criteria

Inclusion criteria: Patients who give consent for the study. Patients requiring fixed orthodontic treatment. Patients with good oral hygiene and healthy periodontium, OHI-S index score in the range of good to fair.

Exclusion criteria

Exclusion criteria: Patients who do not give consent for the study. Patients with compromised periodontium. Patients on antibiotic medications. Patient having systemic illnesses like Diabetes mellites, AIDS, patients on medication like phenytoin, or immunosuppressants. Patients with localized gum disease.

Design outcomes

Primary

Measure	Time frame
Evaluate the antimicrobial property of Conventional Glass Ionomer Cement (GIC), Chitosan (CH) nanoparticles modified Glass Ionomer Cement (GIC) and Chlorhexidine (CLX) modified Glass Ionomer Cement (GIC) for the purpose of cementing orthodontic bands to teeth.Timepoint: Plaque sample collected after 4 weeks from experimental site and control site	—

Secondary

Measure	Time frame
Compare the antimicrobial property of Conventional Glass Ionomer Cement (GIC), Chitosan (CH) nanoparticles modified Glass Ionomer Cement (GIC) and Chlorhexidine (CLX) modified Glass Ionomer Cement (GIC) for the purpose of cementing orthodontic bands to teeth.Timepoint: After completion of 4 weeks, plaque samples will be collected & will be used to check antimicrobial property.	—

Countries

India

Contacts

Public ContactDr Prutha Desai

Manubhai Patel Dental College and Hospital, Vadodara

dr_kalpeshp@yahoo.co.in9898107502

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026