to study the rates of surgical site infections with intraoperative versus long duration post operative prophylactic antibiotic therapy in class 2 luminal gastrointestinal surgeries

Incidence of surgical site infection rates with intraoperative antibiotic prophylaxis vs long duration post operative prophylactic antibiotic therapy in luminal gastrointestinal surgeries : a non inferiority randomized control trial - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081409

Enrollment

104

Registered

2025-02-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: OMISSION OF CONTINUED POST OPERATIVE ANTIBIOTIC THERAPY IN PATIENTS UNDERGOING LUMINAL GASTROINTESTINAL SURGERIES: All patients undergoing luminal gastrointestinal surgeries will receiv

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to give consent to be a participant in this study Patients with at least one month of follow up Patients undergoing luminal gastrointestinal surgeries in elective settings (open and laparoscopic) Patients undergoing surgeries of stomach, small bowel and large bowel(colonic) Patients with class 2 wounds

Exclusion criteria

Exclusion criteria: Patients not consenting to participate in study Patients who have undergone oesophageal surgeries Patients requiring ICU admission during post-operative period Patients who have received blood transfusions during intra-operative period Patients who develop organ failure (requiring mechanical ventilation, requiring pressure support) Patients with an open abdomen (intra -op bogota application) Patients who were operated outside Patients who are lost to follow up, leaving against medical advice or patients who have absconded

Design outcomes

Primary

Measure	Time frame
To assess incidence of surgical site infections in patients receiving intraoperative prophylactic antibiotic dose alone v/s continued post-operative antibiotic prophylaxisTimepoint: 30 days	—

Secondary

Measure	Time frame
To compare the post-operative length of stay. 30-day perioperative morbidity and mortality associated with SSI in the two groups. Timepoint: 30 days	—

Countries

India

Contacts

Public ContactRishika Dhekial Pyrbot

Postgraduate Institute of Medical Education and Research

narayanairrinki@gmail.com9914492255

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026