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Comparison of Albendazole, Mebendazole, Pyrantel pamoate in the treatment and prevention of recurrence of Enterobius vermicularis infection in children - a randomized control trial.

comparison of efficacy of Albendazole, Mebendazole, pyrantel pamoate in achieving remission and preventing recurrence of enterobiusvermicularis infection in children using an objective remission and recurrence score - a randomized control trial. - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081371
Enrollment
105
Registered
2025-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B80- Enterobiasis

Interventions

Intervention1: albendazole: 400mg first dose followed by 2nd dose after 2 weeks Control Intervention1: mebendazole: 100mg 1st dose followed by 2nd dose after 2 weeks Control Intervention2: pyrantel pa

Sponsors

vinayaka missions research foundation deemed to be university
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children in age group of 2-12 years attending the pediatric outpatient department with pin worm infection. pinworm infection is diagnosed by 3 methods 1]pin worms detected on clinical examination 2]parents or attendees accompanying children bring dead or live pinworms 3]pin worms detected by parents and captured on photos or videos stamped with date, time and place(geo tagged).

Exclusion criteria

Exclusion criteria: All the children who already took any of three drugs under study within the past three months

Design outcomes

Primary

MeasureTime frame
occurrence of remission in each of the arm by remission scoreTimepoint: 0 to 8 weeks after initiation of treatment

Secondary

MeasureTime frame
occurrence of recurrence in each of the armTimepoint: 1 to 3 months of remission

Countries

India

Contacts

Public ContactAnnaswamy V Renuka Devi

vinayaka missions medical college and hospital

rajkantmc@gmail.com9080220712

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026